Keeping safe from the risks of multiple (poly) drug use

Multiple (poly) drug use refers to the use of two or more substances in a combination that is intended to achieve a particular effect. It is common amongst problem drug users to have, or to develop, multiple dependencies.

  • DO always try to leave a reasonable period of time between taking additional substances, this will reduce the chances of cross intoxication, therefore, reducing the possibility of an overdose.
  • DO try to consume drugs orally or by smoking, this will reduce the risk of accidental overdose. This may also help to reduce damage to your veins and the risk of transmission of a Blood Borne Virus and/or bacterial infections.
  • DO remember that the majority of drug related deaths occur when depressant, or sedative drugs, and alcohol are combined. Follow the guidance provided with your medication, it is there for a reason.
  • DO remember that over the counter painkillers can contain large amounts of Paracetamol, taking more than the recommended dose can cause damage to your liver and/or kidneys.

  • DO NOT mix multiple depressant drugs such as opiates, benzodiazepines, methadone or alcohol together, doing this will increase your risk of an accidental overdose.
  • DO NOT use stimulant drugs such as cocaine or amphetamines with opiates or benzodiazepines, these combinations can increase the risk of cross intoxication or overdose.
  • DO NOT place yourself, or others, at risk of aggressive or violent behaviour. Do not consume stimulants, benzodiazepines and alcohol together, they can seriously affect your mood and behaviour.
  • DO NOT forget that when your behaviour is influenced by one or more substances, there is a risk of increased sexual activity, you may be less cautious than normal and might take greater risks.
  1. Alcohol Concern

    National agency on alcohol misuse campaigning for effective alcohol policy and improved services for people whose lives are affected by alcohol-related problems

  2. Drink Driving

    Legal advice, information, help, support, news and discussion forum for those that have been caught, convicted of or affected by drink driving

  3. Drink Aware

    Drinkaware provides you with the facts about alcohol…

  4. British Liver Trust

    National charity working to reduce the impact of liver disease in the UK through support , information and research

  5. Urban 75

  6. Alcoholics Anonymous

    AA Great Britain

  7. Cancer Research uk

    The UK's leading cancer charity

  1. Frank

    Aimed mainly at young people also very useful for Parents.

  1. Alcohol Concern

    National agency on alcohol misuse campaigning for effective alcohol policy and improved services for people whose lives are affected by alcohol-related problems

  1. The Zone

    The Zone for support for under 25s

  2. The Eddystone Trust

    the Eddystone Trust HIV / AIDS support and information

  3. FPA

    The family planning association

  4. Brooke Advisory

    Brook advisory centres

  5. Plymouth Hospitals

    The Department of Genito-Urinary Medicine

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